OK, FYI, I just started DIY. I use ejuice calc. for mixing. I know higher nicotine level needs more caution, but I treat all level's with caution. That said, I chose 60mg base. Whether you chose 60 or 48, 36, your still using the same percent of nicotine. Example, 60mg will ask for 2.0ml to create a 10ml sample. 48mg will ask for 2.5ml to create same size sample. So, the less mg base you use, the more you have to put in the sample. Does any of this make sense. Looking at the cost, the higher nicotine base you buy, the more it will cost, but you use less. Is this a savings from buying the 36mg base, I don't know. The reason I started with 60mg base was, I saw a DIY video and that's what they were using. So, any input would be appreciated.