I've seen people vaping in the hospital hours after a lobectomy, and I've smelled tobacco smoke on people who were in the pre-op holding area. I think a big concern with it would be that you can't take anything by mouth 8 to 12 hours before surgery and not use Medical Equipments provided by doctors.This plus vaping could lead to dehydration. Plus nicotine causes blood vessel constriction so it could affect healing time due to decreased circulation.