The lower the resistance, (the fewer coils), the more vapor usually.  
The higher the resistance, (the more coils), the more the flavor usually. 
  
To achieve more flavor: 
1.  Use twisted wire.  (I use 32, some vapers use 30).  Twisted wire means you take a length of wire, fold it in half, tie the ends off, hook it onto a hook.  Place the other loopy end onto a coat hanger, and twist that hanger around nice and consistantly in tension, until it's twisted nicely all the way down the line.  Cut off a piece, and wrap your wick like normal.     This doubles the wire, which doubles the juice, which doubles the flavor.   A lot of peeps use the drill chuck on lowest speed, which works the best for perfect steady tension.  (it twists in a second, so watch out lol!) 
2.  Use flat ribbon wire.  (#6 is popular).  The flat ribbon wire covers more wick area, which theoredically(sp) holds more juice.  It's also great for having less hot spots for some reason.  However, it is a bit trickier to set up.